PRODUCT STRENGTH (CONCENTRATION)
3,4-Dihydro-2H-1-benzopyran-2-one - 250mg/ml
(2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol - 50mg/ml
WHAT ARE THE KEY BENEFITS?
- Food Approved
- Promotes fullness and hardness
- Clinical evidence of activity
- Long acting (blood plasma 1.5hrs, tissue 43 hours)
Androl Y2K is suitable for use by both males and females.
WHAT IS IT?
Androl Y2K is a Myostatin Modulator.
Myostatin is the hormone which balances any negative effects of growth hormone, and encourageshypertrophy (size of skeletal muscle cells) at the expense of hyperplasia (number of skeletal muscle cells).The goal of weight training and supplementation is to safely increase endogenous follistatin, and allow it toinfluence myostatin rather than employ a clinical or research myostatin inhibitor.
Research suggests that myostatin inhibitors currently undergoing research would likely lead to coronary disease. The negative effects ofcomplete myostatin inhibition can be seen in the Belgian Blue, a breed of bovine with no working copy of the gene for myostatin. However97.3% of the cattle are born sterile and 10% die of coronary failure prior to 12 months of age demonstrating that dampening, not inhibition is desirable.
Follistatin modulation, on the other hand, can influence myostatin expression and achieve realistic results without negative effects on longterm health.
New research (2014) has identified a specific chemical in Theobroma species, called (-)-Epicatechin.
(-)-Epicatechin is similar to other polyphenols. However, it carries the unique ability to up-regulate follistatin by 2.5 times and directlydown-regulate myostatin. Moreover, it has also been linked to a lower risk of heart disease. The issue in the past was its low solubility andthus low bioavailability.Androl is a unique solubilised formula allowing a high level of bioavailability.
By modulating myostatin in humans, a reduction in body fat has been demonstrated. Myostatin inhibition thus has two important effects usefulin this context. Increased hyperplasia and muscle mass and decreased adipose tissue. This net effect has been defined as literally anti-aging.One study found that supplementation twice daily with (-)-epicatechin at 50mg led to a 2.5 times increase in follistatin expression within one week.
Dihydrocoumarin is a naturally occurring (in this case nature identical) compound found in Sweet Clover (Melilotus officionalis). Researchconsidered whether dihydrocoumarin could inhibit the human NADþ- dependent deacetylase SIRT1 and observed that DHC induced aconcentration-dependent inhibition of SIRT1 (IC50 of 208 microM) in an in vitro enzymatic assay. That is loosely equivalent to 2400mg for an80kg individual. A decrease in SIRT1 deacetylase activity was observed even at micromolar doses with observed activity at as low as 1.6microM (19mg). The microtubule SIRT2 deacetylase was also inhibited with a similar dose dependency.SIRT1 is a repressor of anabolic and androgenic activity and inhibits DHT mediated transcription thus by inhibiting SIRT1 and SIRT2, anabolicactivates are promoted. SIRT1 inhibition also upregulates androgen receptor expression.
ADMINISTRATION OF PRODUCT
Recommended dosage is 1ml (one full dropper) daily with food, administered in the morning, and mixed into 250ml juice, protein shake, orpre-workout.- For anabolic benefits: 1ml per day, for 30 days
Cycle duration: 30 days
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